PET/computed tomography in chronic lymphocytic leukemia and Richter transformation Review


Authors: Rhodes, J. M.; Mato, A. R.
Review Title: PET/computed tomography in chronic lymphocytic leukemia and Richter transformation
Abstract: Chronic lymphocytic leukemia (CLL)is the most common leukemia in the United States. In 1-10% of cases, it can undergo Richter's transformation (RT)to either diffuse large B cell lymphoma (DLBCL)or Hodgkin's lymphoma (HL). Diagnosis requires histologic confirmation by tissue biopsy. PET/CT has been studied to in several series to look at its predictive value for identifying RT in biopsies. in this review, we will discuss the role of PET/CT to identify RT in patients CLL and its utility in clinical practice. © 2019 Elsevier Inc.
Keywords: pet/ct; chronic lymphocytic leukemia; ibrutinib; richter transformation; venetoclax; accelerated cll; b-cell receptor inhibitor
Journal Title: PET Clinics
Volume: 14
Issue: 3
ISSN: 1556-8598
Publisher: Elsevier Inc.  
Date Published: 2019-07-01
Start Page: 405
End Page: 410
Language: English
DOI: 10.1016/j.cpet.2019.03.007
PROVIDER: scopus
PUBMED: 31084779
DOI/URL:
Notes: Review -- Export Date: 3 June 2019 -- Source: Scopus
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  1. Anthony R Mato
    235 Mato