Psychotropic medication use in parents of children diagnosed with cancer Journal Article


Authors: Salem, H.; Andersen, E. W.; Dalton, S. O.; Schmiegelow, K.; Winther, J. F.; Lichtenthal, W. G.; Johansen, C.; Bidstrup, P. E.
Article Title: Psychotropic medication use in parents of children diagnosed with cancer
Abstract: BACKGROUND: Objective measures on parental distress after a child's cancer diagnosis are sparse. We examined the risk for first prescription of psychotropic medicine among parents of children with cancer compared with parents of children who were cancer free. In addition, we examined if sociodemographic and clinical characteristics are associated with risk of first prescription of psychotropic medication in parents of children with cancer. METHODS: We followed all parents of children with cancer (N = 6744) from the Danish Cancer Registry (1998-2014) using parents of matched children who were cancer free (N = 65 747) as a comparison. To identify vulnerable subgroups among parents of children with cancer, we followed all parents of children with cancer from the Childhood Cancer Registry (2003-2015; N = 3290 parents). In Cox proportional hazard models, we estimated hazard ratios (HRs) for a first prescription of psychotropic medication according to cancer status of the child and sociodemographic and clinical risk factors. RESULTS: Parents of children with cancer were at increased risk for a first prescription of psychotropic medication compared with parents of children who were cancer free up to 2 years after the diagnosis, the risk being highest in the first year (HR, 1.83 [95% confidence interval (CI), 1.66-2.01]). Parents of children with cancer, especially parents who lost their child, had an increased risk for a first prescription of hypnotics (HR, 6.91; 95% CI, 3.50-13.66) and anxiolytics (HR, 4.55, 95% CI, 1.57-13.17) in the first year after diagnosis. CONCLUSIONS: Efforts should be made to ensure that medical teams are adequately educated to address stress responses in the parents. Copyright © 2019 by the American Academy of Pediatrics.
Journal Title: Pediatrics
Volume: 143
Issue: 5
ISSN: 0031-4005
Publisher: American Academy of Pediatrics  
Date Published: 2019-05-01
Start Page: e20182605
Language: English
DOI: 10.1542/peds.2018-2605
PUBMED: 30944153
PROVIDER: scopus
PMCID: PMC7548106
DOI/URL:
Notes: Article -- Export Date: 3 June 2019 -- Source: Scopus
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