Pregnancy as a risk factor for thyroid cancer progression Journal Article


Authors: Rakhlin, L.; Fish, S.
Article Title: Pregnancy as a risk factor for thyroid cancer progression
Abstract: PURPOSE OF REVIEW: The current review evaluates the impact of pregnancy on women with thyroid cancer in three different clinical situations: those with newly diagnosed differentiated thyroid cancer (DTC), those under active surveillance for papillary thyroid microcarcinomas (PMCs), and those with previously treated DTC. RECENT FINDINGS: Recent pregnancy is not associated with high-risk pathological features of DTC. In women with known PMCs under active surveillance, pregnancy does not increase the risk of disease progression. Thus, deferring surgery for newly diagnosed DTC or known PMCs until after delivery is safe for both mother and the unborn child. If a woman with previously treated DTC is planning pregnancy, response-to-therapy status is an excellent guide for predicting pregnancy-associated disease progression or recurrence. SUMMARY: Clinical studies consistently show that pregnancy is not associated with significant disease progression in newly diagnosed thyroid cancer, PMCs under active surveillance, or previously treated DTC.
Journal Title: Current Opinion in Endocrinology, Diabetes and Obesity
Volume: 25
Issue: 5
ISSN: 1752-296X
Publisher: Lippincott Williams & Wilkins  
Date Published: 2018-10-01
Start Page: 326
End Page: 329
Language: English
DOI: 10.1097/med.0000000000000424
PUBMED: 29965867
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 3 June 2019 -- Source: Scopus