Authors: | Jansen, J. F. A.; Gearhart, J. D.; Bulte, J. W. M. |
Article Title: | Comment on "Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain" |
Abstract: | Manganas et al. (Reports, 9 November 2007, p. 980) reported the discovery of a biomarker specific for neural progenitor cells detectable using magnetic resonance spectroscopy. A new algorithm was developed to extract the biomarker from noisy in vivo data. We question how this algorithm was validated, because the biomarker overlaps with peaks from nonspecific lipid signals. |
Keywords: | nonhuman; note; methodology; biological marker; biological markers; mouse; animal; cytology; animals; mice; embryonic stem cell; lipid; signal noise ratio; neurons; algorithms; stem cell; depression; chemistry; algorithm; brain; magnetic resonance spectroscopy; nuclear magnetic resonance spectroscopy; stem cells; embryonic stem cells; lipids; nervous system development; nerve cell; mood disorder; hippocampus |
Journal Title: | Science |
Volume: | 321 |
Issue: | 5889 |
ISSN: | 0036-8075 |
Publisher: | American Association for the Advancement of Science |
Date Published: | 2008-08-01 |
Start Page: | 640 |
Language: | English |
DOI: | 10.1126/science.1153997 |
PUBMED: | 18669846 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 3" - "Export Date: 17 November 2011" - "CODEN: SCIEA" - "Source: Scopus" |