Comment on "Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain" Journal Article


Authors: Jansen, J. F. A.; Gearhart, J. D.; Bulte, J. W. M.
Article Title: Comment on "Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain"
Abstract: Manganas et al. (Reports, 9 November 2007, p. 980) reported the discovery of a biomarker specific for neural progenitor cells detectable using magnetic resonance spectroscopy. A new algorithm was developed to extract the biomarker from noisy in vivo data. We question how this algorithm was validated, because the biomarker overlaps with peaks from nonspecific lipid signals.
Keywords: nonhuman; note; methodology; biological marker; biological markers; mouse; animal; cytology; animals; mice; embryonic stem cell; lipid; signal noise ratio; neurons; algorithms; stem cell; depression; chemistry; algorithm; brain; magnetic resonance spectroscopy; nuclear magnetic resonance spectroscopy; stem cells; embryonic stem cells; lipids; nervous system development; nerve cell; mood disorder; hippocampus
Journal Title: Science
Volume: 321
Issue: 5889
ISSN: 0036-8075
Publisher: American Association for the Advancement of Science  
Date Published: 2008-08-01
Start Page: 640
Language: English
DOI: 10.1126/science.1153997
PUBMED: 18669846
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 3" - "Export Date: 17 November 2011" - "CODEN: SCIEA" - "Source: Scopus"
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  1. Jacobus Jansen
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