The diagnostic accuracy of dermoscopy for basal cell carcinoma: A systematic review and meta-analysis Review

  


Authors: Reiter, O.; Mimouni, I.; Gdalevich, M.; Marghoob, A. A.; Levi, A.; Hodak, E.; Leshem, Y. A.
Review Title: The diagnostic accuracy of dermoscopy for basal cell carcinoma: A systematic review and meta-analysis
Abstract: Background: Dermoscopy is a noninvasive technique for the diagnosis of skin lesions. Its accuracy for basal cell carcinoma (BCC) has not been systematically studied. Objective: We sought to systematically investigate the accuracy of dermoscopy for the diagnosis of BCC compared with examination with the naked eye. Methods: A systematic review of studies reporting the accuracy of naked eye examination and dermoscopy for the diagnosis of BCC was conducted. A meta-analysis for sensitivity and specificity was performed using a bivariate mixed-effects logistic regression modeling framework. Results: Seventeen studies were identified. The pooled sensitivity and specificity of dermoscopy for the diagnosis of BCC were 91.2% and 95%, respectively. In studies comparing test performance, adding dermoscopy to naked eye examination improved sensitivity from 66.9% to 85% (P =.0001) and specificity from 97.2% to 98.2% (P =.006). The sensitivity and specificity of dermoscopy were higher for pigmented than nonpigmented BCC. Sensitivity increased when dermoscopy was performed by experts and when the diagnosis was based on in-person dermoscopy as opposed to dermoscopic photographs. Limitations: Significant heterogeneity among studies with a medium-to-high risk of bias. Conclusion: Dermoscopy is a sensitive and specific add-on tool for the diagnosis of BCC. It is especially valuable for pigmented BCC. © 2018 American Academy of Dermatology, Inc.
Keywords: dermoscopy; basal cell carcinoma; dermatoscopy
Journal Title: Journal of the American Academy of Dermatology
Volume: 80
Issue: 5
ISSN: 0190-9622
Publisher: Mosby Elsevier  
Date Published: 2019-05-01
Start Page: 1380
End Page: 1388
Language: English
DOI: 10.1016/j.jaad.2018.12.026
PUBMED: 30582991
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063096163&doi=10.1016%2fj.jaad.2018.12.026&partnerID=40&md5=af8036f29743271443b8ffa8d153faad
Notes: Article -- Export Date: 1 May 2019 -- Source: Scopus
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MSK Authors
  1. Ashfaq A Marghoob
    534 Marghoob
  2. Ofer Reiter Agar
    15 Reiter Agar
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