Hair disorders in patients with cancer Journal Article

   


Authors: Freites-Martinez, A.; Shapiro, J.; Goldfarb, S.; Nangia, J.; Jimenez, J. J.; Paus, R.; Lacouture, M. E.
Article Title: Hair disorders in patients with cancer
Abstract: Cytotoxic chemotherapies, molecularly targeted therapies, immunotherapies, radiotherapy, stem cell transplants, and endocrine therapies may lead to hair disorders, including alopecia, hirsutism, hypertrichosis, and pigmentary and textural hair changes. The mechanisms underlying these changes are varied and remain incompletely understood, hampering the development of preventive or therapeutic guidelines. The psychosocial impact of chemotherapy-induced alopecia has been well documented primarily in the oncology literature; however, the effect of other alterations, such as radiation-induced alopecia, hirsutism, and changes in hair color or texture on quality of life have not been described. This article reviews clinically significant therapy-related hair disorders in oncology patients, including the underlying pathophysiological mechanisms, severity grading scales, patient-reported quality of life questionnaires, management strategies, and future translational research opportunities. © 2018 American Academy of Dermatology, Inc.
Keywords: hyperpigmentation; hypopigmentation; hypertrichosis; depigmentation; trichomegaly; hirsutism; cancer patients; chemotherapy-induced alopecia; anagen effluvium; brittleness; catagen effluvium; curling; eyebrow alopecia; eyelash alopecia; hair repigmentation; straightening
Journal Title: Journal of the American Academy of Dermatology
Volume: 80
Issue: 5
ISSN: 0190-9622
Publisher: Mosby Elsevier  
Date Published: 2019-05-01
Start Page: 1179
End Page: 1196
Language: English
DOI: 10.1016/j.jaad.2018.03.055
PROVIDER: scopus
PMCID: PMC6186204
PUBMED: 29660422
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064251910&doi=10.1016%2fj.jaad.2018.03.055&partnerID=40&md5=56bd06149612f4fe58e9b3ce653e1555
Notes: Review -- Export Date: 1 May 2019 -- Source: Scopus
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MSK Authors
  1. Mario E Lacouture
    457 Lacouture
  2. Shari Goldfarb
    151 Goldfarb
  3. Azael David Freites Martinez
    29 Freites Martinez
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