A comparison of white-light cystoscopy and narrow-band imaging cystoscopy to detect bladder tumour recurrences Journal Article
| Authors: | Herr, H. W.; Donat, S. M. |
| Article Title: | A comparison of white-light cystoscopy and narrow-band imaging cystoscopy to detect bladder tumour recurrences |
| Abstract: | OBJECTIVE: To determine whether narrow-band imaging (NBI) cystoscopy enhances the detection of non-muscle-invasive bladder tumours over standard white-light imaging (WLI) cystoscopy, as surveillance WLI is the standard method used to diagnose patients with recurrent bladder tumours, but they can be missed by WLI cystoscopy, possibly accounting for early recurrences. PATIENTS AND METHODS: We evaluated 427 patients for recurrent bladder tumours by WLI cystoscopy, followed by NBI cystoscopy as a further procedure, using the same video-cystoscope. Recurrent tumours visualized by WLI or NBI cystoscopy were mapped, imaged, biopsied and subsequently treated by transurethral resection (TUR) or fulguration. Biopsies or TUR specimens obtained by WLI and NBI were examined separately for presence of tumour. RESULTS: In all, 103 patients (24%) had tumour recurrences; 90 (87%) were detected by both WLI and NBI and another 13 (100%) only by NBI cystoscopy. NBI detected extra papillary tumours or more extensive carcinoma in situ in 58 (56%) patients found to have recurrences. The mean number of recurrent tumours visualized on WLI cystoscopy was 2.3, vs to 3.4 seen on NBI cystoscopy (P = 0.01). CONCLUSION: NBI cystoscopy improved the detection of recurrent non-muscle-invasive bladder tumours over standard WLI cystoscopy. © 2008 The Authors. |
| Keywords: | adult; controlled study; human tissue; aged; aged, 80 and over; middle aged; surgical technique; major clinical study; histopathology; cancer recurrence; cancer diagnosis; sensitivity and specificity; prospective studies; cohort studies; neoplasm recurrence, local; recurrence; diagnostic imaging; urinary bladder neoplasms; imaging system; image enhancement; intermethod comparison; cystoscopy; transurethral resection; bladder carcinoma; narrow-band imaging; light; bladder tumours; bladder biopsy; cauterization; narrow band imaging cystoscopy; white light cystoscopy |
| Journal Title: | BJU International |
| Volume: | 102 |
| Issue: | 9 |
| ISSN: | 1464-4096 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2008-11-01 |
| Start Page: | 1111 |
| End Page: | 1114 |
| Language: | English |
| DOI: | 10.1111/j.1464-410X.2008.07846.x |
| PUBMED: | 18778359 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 42" - "Export Date: 17 November 2011" - "CODEN: BJINF" - "Source: Scopus" |
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