Authors: | Gonzalez, S.; Fernández-Lorente, M.; Gilaberte-Calzada, Y. |
Article Title: | The latest on skin photoprotection |
Abstract: | UV radiation is the main etiological agent of most types of skin cancer and a key factor responsible for photoaging. Photoprotection is thus critical to avoid these undesired effects. Sunscreens rank among the best photoprotective measures. Sunscreens are the main components of lotions and creams used to prevent UV-induced damage or to ameliorate its harmful effects. There are 3 types of sunscreens: physical photon blockers, antioxidants, and stimulators of repairing mechanisms. This review summarizes current topics in the development of sunscreens, with special emphasis on substances of natural origin bearing photoscreening, antioxidant, or repairing properties. The characterization of different parameters to evaluate the effects of sunscreens, such as the sunscreen protection factor, is discussed. Finally, the effect of public awareness and public health campaigns are also reviewed. © 2008 Elsevier Inc. All rights reserved. |
Keywords: | unclassified drug; clinical trial; placebo; drug safety; nonhuman; sunscreen; unindexed drug; low drug dose; protective clothing; enzyme inhibition; sun exposure; skin cancer; radiation injury; quercetin; cytotoxic t lymphocyte; erythema; single drug dose; health promotion; omega 3 fatty acid; antioxidant; antioxidants; alpha tocopherol; ascorbic acid; antioxidant activity; lycopene; epigallocatechin gallate; drug absorption; immunity; ultraviolet a radiation; ultraviolet b radiation; awareness; resveratrol; cell protection; oligonucleotide; sunscreening agents; tissue repair; polyglactin; sunlight protection; sunburn; polypodium leucotomos extract; photoaging; radiation protection; skin aging; skin inflammation; langerhans cell; contact dermatitis; skin protection; carotenoid; genistein; apigenin; astaxanthin; avobenzone; equol; ferulic acid; oxybenzone; titanium dioxide; zinc oxide; spectacles; mexoryl sx; silymarin; hormone action; 4 methoxycinnamic acid 2 ethylhexyl ester; drometrizol trisiloxane; eusolex 4360; mexoryl xl; physical photon blocker; seresis; terephtalylidene dicamphor sulfonic acid; mutagenicity; skin penetration |
Journal Title: | Clinics in Dermatology |
Volume: | 26 |
Issue: | 6 |
ISSN: | 0738-081X |
Publisher: | Elsevier Inc. |
Date Published: | 2008-11-01 |
Start Page: | 614 |
End Page: | 626 |
Language: | English |
DOI: | 10.1016/j.clindermatol.2007.09.010 |
PUBMED: | 18940542 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 36" - "Export Date: 17 November 2011" - "CODEN: CLDEE" - "Source: Scopus" |