Authors: | Isaacs, R. C. A.; Di Grandi, M. J.; Danishefsky, S. J. |
Article Title: | Synthesis of an enantiomerically pure intermediate containing the CD substructure of taxol |
Abstract: | A straightforward conversion of the (R)-(−)-Hajos-Parrish ketone 5 to oxetane 13 is reported. It is anticipated that intermediates related to this compound could be useful for the total synthesis of taxol. © 1993, American Chemical Society. All rights reserved. |
Keywords: | paclitaxel; drug synthesis; taxane derivative; reaction analysis; stereochemistry; circular dichroism; article |
Journal Title: | Journal of Organic Chemistry |
Volume: | 58 |
Issue: | 15 |
ISSN: | 0022-3263 |
Publisher: | American Chemical Society |
Date Published: | 1993-07-01 |
Start Page: | 3938 |
End Page: | 3941 |
Language: | English |
DOI: | 10.1021/jo00067a028 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 1 March 2019 -- Source: Scopus |