Diagnostic pitfalls in fine needle aspiration biopsy of the spleen Journal Article

  


Authors: Friedlander, M. A.; Wei, X. J.; Iyengar, P.; Moreira, A. L.
Article Title: Diagnostic pitfalls in fine needle aspiration biopsy of the spleen
Abstract: Fine needle aspiration (FNA) of the spleen is rarely performed, due to fear of procedure complications. The objective of this study is to review the cytologic diagnoses of aspiration biopsy of the spleen performed in a cancer center. Archival material (9-year period) was reviewed and correlated with histologic and ancillary test results, when available. Forty-one splenic FNA specimens were identified. There were no reported procedure complications. Nineteen cases were diagnosed as malignant. Of these, 11 were lymphomas. Nineteen cases were diagnosed as benign. There was one false-negative case and four false-positive cases. Primary splenic neoplasms were rare and misinterpreted as malignant. It is important to be familiar with the normal cytology of this uncommonly aspirated organ in order to successfully identify neoplastic and malignant processes. The use of ancillary studies is important in the definitive classification of benign and malignant splenic lesions. © 2008 Wiley-Liss, Inc.
Keywords: adolescent; adult; child; aged; aged, 80 and over; middle aged; retrospective studies; histopathology; review; cytology; spleen; diagnosis, differential; false negative result; correlation analysis; diagnostic value; diagnostic errors; biopsy, fine-needle; lymphoma; aspiration biopsy; false positive result; false positive reactions; false negative reactions; spleen tumor; splenic neoplasms; cytodiagnosis; information center; spleen cancer
Journal Title: Diagnostic Cytopathology
Volume: 36
Issue: 2
ISSN: 8755-1039
Publisher: Wiley Liss  
Date Published: 2008-02-01
Start Page: 69
End Page: 75
Language: English
DOI: 10.1002/dc.20749
PUBMED: 18181188
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-38549093518&partnerID=40&md5=d291f38bc5189b0fec88b8e8777cd1c2
Notes: --- - "Cited By (since 1996): 3" - "Export Date: 17 November 2011" - "CODEN: DICYE" - "Source: Scopus"
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MSK Authors
  1. Andre L Moreira
    176 Moreira
  2. Maria Friedlander
    43 Friedlander
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