Short-term morbidity from CT-planned transperineal I-125 prostate implants Journal Article
| Authors: | Arterbery, V. E.; Wallner, K.; Roy, J.; Fuks, Z. |
| Article Title: | Short-term morbidity from CT-planned transperineal I-125 prostate implants |
| Abstract: | Purpose: To summarize short-term morbidity and tumor response following transperineal transperineal CT-guided I-125 prostate implantation. Methods and Materials: Twenty-one patients were treated with CT-based transperineal 1-125 prostate implantation between June, 1988 and May, 1990. An average of 75 I-125 seeds were placed, with an average activity of .62 mCi/seed. Symptoms were quantified after interviewing each patient in detail. Results: Nearly all patients developed substantial dysuria, nocturia and frequency from 2-24 weeks following implantation. Urinary symptoms usually resolved within 4-6 months of implantation. The one year actuarial potency rate among 18 patients who were potent prior to implantation was 94%. By 6 months after implantation, 14 17 patients (82%) with Stage B tumors had complete regression of palpable disease. Of 17 patients with Stage A or B tumors who presented with an elevated PSA, 76% returned to the normal range within 6 months of implantation. Conclusion: CT-guided transperineal prostate implants entail moderate, temporary urinary and rectral morbidity. Short-term tumor responses are encouraging. © 1993. |
| Keywords: | clinical article; diarrhea; follow-up studies; neoplasm staging; prostate specific antigen; computer assisted tomography; morbidity; tomography, x-ray computed; radiation injury; time factors; prostatic neoplasms; cancer regression; iodine 125; brachytherapy; impotence; computed tomography; dysuria; prostate carcinoma; rectum hemorrhage; ejaculation; proctitis; nocturia; iodine-125; urination disorders; terazosin; prostatic carcinoma; phenazopyridine; human; male; priority journal; article; rectum ulcer; support, non-u.s. gov't |
| Journal Title: | International Journal of Radiation Oncology, Biology, Physics |
| Volume: | 25 |
| Issue: | 4 |
| ISSN: | 0360-3016 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1993-03-15 |
| Start Page: | 661 |
| End Page: | 667 |
| Language: | English |
| DOI: | 10.1016/0360-3016(93)90013-l |
| PUBMED: | 8454484 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 March 2019 -- Source: Scopus |
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