Treatment‐related esophageal stricture in pediatric patients with cancer Journal Article
| Authors: | Ellenhorn, J. D. I.; Lambroza, A.; Lindsley, K. L.; Laquaglia, M. P. |
| Article Title: | Treatment‐related esophageal stricture in pediatric patients with cancer |
| Abstract: | Background. Intensive antineoplastic regimens have enhanced long‐term survival in pediatric patients with cancer, but can result in long‐term complications. Esophageal stricture formation is one such complication. Methods. We reviewed the experience with benign esophageal stricture in pediatric patients with cancer over the past 15 years in a major cancer center. Clinical course, along with endoscopic, radiologic, and manometric esophageal studies, was reviewed. Results. Esophageal strictures formed in five pediatric patients who were treated with radiation and/or chemotherapy. Stricture formation was associated with abnormal esophageal motility in four out of the five patients. Repeated esophageal dilation was performed from 3–50 times and resulted in stricture resolution in only 2 of the 5 patients. Conclusions. Esophageal stricture formation in this population is rare, but is associated with long‐term morbidity. Copyright © 1993 American Cancer Society |
| Keywords: | cancer chemotherapy; cancer survival; child; clinical article; child, preschool; case report; antineoplastic agents; cancer radiotherapy; combined modality therapy; antineoplastic agent; neoplasms; esophagitis; antineoplastic combined chemotherapy protocols; cancer therapy; childhood cancer; hodgkin disease; radiation injuries; complications; radiation therapy; rhabdomyosarcoma; children; esophagus stricture; esophageal neoplasms; oropharyngeal neoplasms; leukemia, lymphocytic, acute; palatal neoplasms; esophageal stenosis; tracheal neoplasms; esophagus dilatation; human; male; female; priority journal; article; manometry; esophageal motility disorders; esophagus motility |
| Journal Title: | Cancer |
| Volume: | 71 |
| Issue: | 12 |
| ISSN: | 0008-543X |
| Publisher: | Wiley Blackwell |
| Date Published: | 1993-06-15 |
| Start Page: | 4084 |
| End Page: | 4090 |
| Language: | English |
| DOI: | 10.1002/1097-0142(19930615)71:12<4084::Aid-cncr2820711246>3.0.Co;2-b |
| PUBMED: | 8508373 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
