Use of PSA-NCAM in repair of the central nervous system Journal Article

  


Authors: El-Maarouf, A. ; Rutishauser, U.
Article Title: Use of PSA-NCAM in repair of the central nervous system
Abstract: Polysialic acid (PSA) is a highly hydrated polymer whose presence at the cell surface can reduce cell interactions, and thereby increase tissue and cellular plasticity. Given its ability to create a permissive environment for cell migration and axonal growth, the potential of engineered over-expression of PSA to promote tissue repair has been explored in the adult CNS. Several promising results have been obtained that suggest that PSA engineering may become a valuable therapeutic tool. © 2008 Springer Science+Business Media, LLC.
Keywords: regeneration; polysialic acid; stem cells; plasticity; brain lesion
Journal Title: Neurochemical Research
ISSN: 0364-3190
Publisher: Springer  
Date Published: 2008-01-01
Start Page: 1
End Page: 7
Language: English
DOI: 10.1007/s11064-008-9635-7
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-40449083161&partnerID=40&md5=9cebf6fb4cd478c67e6dfd9e10190414
Notes: --- - "Cited By (since 1996): 4" - "Export Date: 17 November 2011" - Article in Press - "CODEN: NERED" - "Source: Scopus"
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MSK Authors
  1. Urs S Rutishauser
    70 Rutishauser
  2. Abderrahman El Maarouf
    22 El Maarouf
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