Nipple-sparing mastectomy: Where are we now? Journal Article


Authors: Chung, A. P.; Sacchini, V.
Article Title: Nipple-sparing mastectomy: Where are we now?
Abstract: Surgical treatment of breast cancer has evolved from radical mastectomy with routine removal of the nipple-areolar complex (NAC) to breast conservative therapy with preservation of the breast and NAC. When breast conservation is not appropriate or the patient desires mastectomy for risk reduction, conventional therapy still consists of mastectomy with removal of the NAC, followed by reconstruction. Rising interest in improved cosmesis has led to the introduction of the skin-sparing and nipple-sparing mastectomy (NSM) as potential alternatives to mastectomy. There has been much controversy regarding the oncologic safety of these procedures, and the NSM has also introduced a set of complications, such as nipple and areolar necrosis, that are not a concern with total mastectomy. From our review of the literature, we feel that NSM may be a viable option in the appropriate setting, and that its risks and complications are acceptable when compared to the traditional surgical treatment of breast cancer. © 2008 Elsevier Ltd. All rights reserved.
Keywords: treatment outcome; cancer surgery; surgical technique; review; cancer staging; breast cancer; mastectomy; breast neoplasms; risk factor; risk assessment; conservative treatment; safety; mastectomy, subcutaneous; nipples; risk reduction; nipple-sparing mastectomy; breast areola; nipple sparing mastectomy; breast necrosis; nipple-areolar complex preservation
Journal Title: Surgical Oncology
Volume: 17
Issue: 4
ISSN: 0960-7404
Publisher: Elsevier Inc.  
Date Published: 2008-12-01
Start Page: 261
End Page: 266
Language: English
DOI: 10.1016/j.suronc.2008.03.004
PUBMED: 18456492
PROVIDER: scopus
DOI/URL:
Notes: Erratum/Corrigendum issued, see DOI: 10.1016/j.suronc.2009.11.004 -- "Cited By (since 1996): 16" - "Export Date: 17 November 2011" - "CODEN: SUOCE" - "Source: Scopus"
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  1. Virgilio Sacchini
    147 Sacchini
  2. Alice Ping Chung
    4 Chung