Sulforaphane, an extract from broccoli, prevents skin cancer Journal Article

  


Authors: Chen, Y. J. D.; Conte, J.; Lin, Y.; Gemelli, A.; Castro, A.; Yarlagadda, S.; Gonzalez, S.; Philips, N.
Article Title: Sulforaphane, an extract from broccoli, prevents skin cancer
Abstract: Sulforaphane is a natural, biologically active compound extracted from cruciferous vegetables such as broccoli and cabbage. Sulforaphane is a chemopreventive agent against the development and proliferation of cancers. Aside from its chemopreventive effects, SFN is also a potential therapeutic anticancer agent; it induces cell cycle arrest and apoptosis in human cancer cells. Sulforaphane enhances protective and detoxifying reactions in skin cells, and it also assists in repairing damage already done to skin that has been exposed to the sun.
Keywords: antineoplastic agent; ultraviolet radiation; cancer prevention; apoptosis; sun exposure; skin cancer; drug structure; cancer cell; cell cycle arrest; natural killer cell; detoxification; tissue repair; lymphocyte function; skin cell; carcinogen; xenobiotic agent; anti-carcinogenic; broccoli; phase ii enzymes; sulforaphane; transcription factor nrf2
Journal Title: Journal of Plastic Dermatology
Volume: 4
Issue: 2
ISSN: 1473-2130
Publisher: International-Italian Society of Plastic and Oncologic Dermatology  
Date Published: 2008-01-01
Start Page: 165
End Page: 166
Language: English
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-55449115593&partnerID=40&md5=227550cf6057fa89b543ec05ff87b96b
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 17 November 2011" - "Source: Scopus"