The incidence of venous thromboembolism after oncologic head and neck reconstruction Journal Article


Authors: Chen, C.; Disa, J.; Cordeiro, P.; Pusic, A.; Mccarthy, C.; Mehrara, B.
Article Title: The incidence of venous thromboembolism after oncologic head and neck reconstruction
Abstract: This study evaluates the incidence of symptomatic deep venous thrombosis and pulmonary embolism after head and neck reconstruction at a single tertiary care cancer center. From 1997 to 2006, 6,759 surgical procedures were performed. There were 1,591 head and neck reconstructions (n = 1,591) and 5,168 non-head and neck reconstructions (n = 5,168). Free flaps, regional flaps, and other procedures were included. Although the incidence of venous thromboembolism (VTE) was less than 1% in both patient populations, there was a significantly greater incidence of VTE among patients undergoing head and neck reconstruction than non-head and neck reconstruction (P < 0.05). When compared with patients undergoing non-head and neck reconstruction, patients undergoing oncologic head and neck procedures were older, underwent longer anesthesia times, spent more days in the hospital, and were more likely to need free flaps. When possible, appropriate prophylaxis against VTE in cancer patients under going head and neck reconstruction is recommended. © 2008 Lippincott Williams & Wilkins, Inc.
Keywords: adolescent; adult; cancer chemotherapy; child; aged; aged, 80 and over; child, preschool; middle aged; surgical technique; reconstructive surgical procedures; retrospective studies; major clinical study; head and neck surgery; surgical flaps; conference paper; cancer patient; cancer radiotherapy; incidence; oncology; lung embolism; pulmonary embolism; cancer center; hospitalization; statistical significance; head and neck cancer; head and neck neoplasms; acetylsalicylic acid; prophylaxis; free tissue graft; reconstruction; head and neck; low molecular weight heparin; venous thromboembolism; deep venous thrombosis; reconstructive surgery; anesthesia induction
Journal Title: Annals of Plastic Surgery
Volume: 60
Issue: 5
ISSN: 0148-7043
Publisher: Lippincott Williams & Wilkins  
Date Published: 2008-05-01
Start Page: 476
End Page: 479
Language: English
DOI: 10.1097/SAP.0b013e31816fd7e7
PUBMED: 18434817
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 5" - "Export Date: 17 November 2011" - "CODEN: APCSD" - "Source: Scopus"
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MSK Authors
  1. Joseph Disa
    254 Disa
  2. Andrea Pusic
    299 Pusic
  3. Constance M Chen
    16 Chen
  4. Babak Mehrara
    400 Mehrara
  5. Peter G Cordeiro
    278 Cordeiro
  6. Colleen Marie McCarthy
    135 McCarthy