Hepatoma registry of the Western world Journal Article


Authors: Tsao, J. I.; Asbun, H. J.; Hughes, K. S.; other members of the Repeat Hepatic Resection Registry
Contributors: Fortner, J.; Maclean, B.
Article Title: Hepatoma registry of the Western world
Abstract: The western HCC registry comprised data from 322 patients who underwent hepatic resection for HCC over a 50-year period. The majority of patients had lesions > 4 cm and were symptomatic at presentation. Lesions were mostly unicentric. Cirrhosis was not a prevalent problem, unlike the East. In the most recent decade, 1980-1989, we noted a significant decrease in operative mortality from 19% to 10% overall, and 15% to 4% in the noncirrhotic group. We identified four variables that resulted in poorer postresectional outcome: cirrhosis, regional nodal disease, multicentric disease, and tumor-free resectional margin < 1 cm. Although these factors are associated with a poorer outcome after resection, whether they should serve as contraindications to surgery should be determined by individual surgeons, taking into account the patient's overall status, concomitant risk factors, and treatment objectives.
Keywords: adolescent; adult; aged; aged, 80 and over; middle aged; liver cell carcinoma; carcinoma, hepatocellular; liver neoplasms; united states; pathology; register; registries; liver tumor; reoperation; germany; humans; prognosis; human; male; female; article
Journal Title: Cancer Treatment and Research
Volume: 69
ISSN: 0927-3042
Publisher: Springer  
Date Published: 1994-01-01
Start Page: 21
End Page: 31
Language: English
PUBMED: 8031652
PROVIDER: scopus
DOI/URL:
Notes: Chapter 3 in "Hepatobiliary Cancer" (ISBN: 0-7923-2501-X) -- Export Date: 15 February 2019 -- Source: Scopus
Citation Impact
MSK Authors
  1. Joseph G Fortner
    38 Fortner