Intensity-modulated radiation therapy: Supportive data for prostate cancer Journal Article

  


Authors: Cahlon, O.; Hunt, M.; Zelefsky, M. J.
Article Title: Intensity-modulated radiation therapy: Supportive data for prostate cancer
Abstract: Since its introduction into clinical use in the mid-1990s, intensity-modulated radiation therapy (IMRT) has emerged as the most effective and widely used form of external-beam radiotherapy for localized prostate cancer. Multiple studies have confirmed the importance of delivering sufficiently high doses to the prostate to achieve cure. The dosimetric superiority of IMRT over conventional techniques to produce conformal dose distributions that allow for organ sparing has been shown. A growing number of reports have confirmed that IMRT is the safest way to deliver high doses of external-beam irradiation to the prostate and the regional lymph nodes. Advances in imaging and onboard verification systems continue to advance the capabilities of IMRT and have potential implications with regards to further dose escalation and hypofractionated regimens. The clinical data in support of IMRT and the associated technical aspects of IMRT treatment planning and implementation are highlighted in this review. © 2008 Elsevier Inc. All rights reserved.
Keywords: clinical trial; intensity modulated radiation therapy; treatment planning; pelvis lymph node; nephrotoxicity; radiotherapy dosage; prostate cancer; prostatic neoplasms; gastrointestinal toxicity; radiotherapy, intensity-modulated; dosimetry; lymph node; data analysis; external beam radiotherapy; radiation dose distribution; lymphatic irradiation
Journal Title: Seminars in Radiation Oncology
Volume: 18
Issue: 1
ISSN: 1053-4296
Publisher: Elsevier Inc.  
Date Published: 2008-01-01
Start Page: 48
End Page: 57
Language: English
DOI: 10.1016/j.semradonc.2007.09.007
PUBMED: 18082588
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-36849079824&partnerID=40&md5=3ae79fc2be8286857099f0b93ee63683
Notes: --- - "Cited By (since 1996): 43" - "Export Date: 17 November 2011" - "CODEN: SRONE" - "Source: Scopus"
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MSK Authors
  1. Michael J Zelefsky
    754 Zelefsky
  2. Oren Cahlon
    158 Cahlon
  3. Margie A Hunt
    287 Hunt
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