Allograft reconstruction after proximal tibial resection for bone tumors: An analysis of function and outcome comparing allograft and prosthetic reconstructions Journal Article


Authors: Brien, E. W.; Terek, R. M.; Healey, J. H.; Lane, J. M.
Article Title: Allograft reconstruction after proximal tibial resection for bone tumors: An analysis of function and outcome comparing allograft and prosthetic reconstructions
Abstract: Seventeen patients (age, 12-63 years; median, 22 years) treated with proximal tibial allografts were identified. Nine cases were intercalary and eight were osteoarticular allografts. Complications, number of operations, and oncologic and functional results were reviewed. The functional results of the allografts were compared with a prior cohort of patients who had endoprosthesis at the same institution by the same surgeons. There were 14 malignant tumors, two benign aggressive tumors, and one sclerosing osteomyelitis mimicking osteosarcoma. Twelve of 17 patients had complications, the most common being fracture, deformity, and infection. Six patients required more than one procedure, and three had amputations after allograft reconstruction. The ultimate function was excellent in three patients, good in seven, fair in six, and poor in one. There were 14 patients with endoprosthetic reconstruction. Wound problems followed by prosthetic loosening were the most common complications. Of the eight patients requiring a second procedure, three had an amputation. Three had excellent, seven good, and four fair functional results at the final evaluation. No patient in either group had a local recurrence. Allograft provides an alternative to endoprosthetic reconstruction; however, the high incidence of complications makes the outcome unpredictable. Allograft or prosthetic reconstruction provides better functional results than amputation without sacrificing oncologic results.
Keywords: transplantation; dogs; knee; management; model; grafts
Journal Title: Clinical Orthopaedics and Related Research
Volume: 303
ISSN: 0009-921X
Publisher: Springer  
Date Published: 1994-06-01
Start Page: 116
End Page: 127
Language: English
ACCESSION: WOS:A1994NP39100014
PROVIDER: wos
PUBMED: 8194221
Notes: Source: Wos
Citation Impact
MSK Authors
  1. John H Healey
    547 Healey
  2. Joseph M. Lane
    66 Lane