A hitherto unreported pulmonary complication in an IV heroin user Journal Article


Authors: Bishay, A.; Amchentsev, A.; Saleh, A.; Patel, N.; Travis, W.; Raoof, S.
Article Title: A hitherto unreported pulmonary complication in an IV heroin user
Abstract: IV heroin use is associated with several well-described complications, including noncardiogenic pulmonary edema, aspiration pneumonitis, ARDS, pneumonia, lung abscess, septic pulmonary emboli, and atelectasis. Foreign-body granulomatosis may develop when drug users inject solutions containing crushed oral tablets in which talc is used as filler and can be complicated by pulmonary fibrosis. The effects are distinct from pulmonary edema, which may occur acutely with heroin injection. We describe the case of a young female patient who was an IV heroin user who also smoked cigarettes, and presented with progressive dyspnea, hypoxia, and bilateral lung infiltrates. The final pathologic diagnosis in this case was one that had not been previously reported in IV heroin users.
Keywords: adult; histopathology; case report; cigarette smoking; computer assisted tomography; tomography, x-ray computed; dyspnea; hypoxia; depression; atelectasis; interstitial lung disease; physical examination; methadone; drug abuse; cotrimoxazole; lung fibrosis; fluoxetine; lung infiltrate; aspiration pneumonia; diamorphine; adult respiratory distress syndrome; lung complication; trazodone; lung edema; bronchiolitis obliterans; lung pathology; foreign body granuloma; heroin dependence; intravenous drug abuse; pneumocystis jiroveci; bronchiolitis obliterans organizing pneumonia; granuloma, foreign-body; substance abuse, intravenous
Journal Title: Chest
Volume: 133
Issue: 2
ISSN: 0012-3692
Publisher: American College of Chest Physicians  
Date Published: 2008-02-01
Start Page: 549
End Page: 551
Language: English
DOI: 10.1378/chest.07-0805
PUBMED: 18252922
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 17 November 2011" - "CODEN: CHETB" - "Source: Scopus"
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  1. William D Travis
    743 Travis