Acute promyelocytic leukemia - The author's reply Journal Article

  


Authors: Warrell, R. P. Jr; Degos, L.
Article Title: Acute promyelocytic leukemia - The author's reply
Abstract: To the Editor: Warrell et al. (July 15 issue)1 do an excellent job of correlating the molecular and clinical aspects of acute promyelocytic leukemia. Less convincing, however, is their attribution of a “syndrome characterized by fever, respiratory distress, radiographic pulmonary infiltrates, pleural effusions, and weight gain” with “extensive infiltration of myeloid cells” to the administration of all-trans-retinoic acid. Before retinoic acid was used in the treatment of acute promyelocytic leukemia, fever and pulmonary manifestations of capillary leakage were described in patients with acute myeloid leukemia with or without hyperleukocytosis2,3 and ascribed to the invasiveness of promyeloblasts or the release... © 1994, Massachusetts Medical Society. All rights reserved.
Keywords: adult; clinical feature; case report; cytarabine; letter; fever; leukemia, promyelocytic, acute; syndrome; acute myeloblastic leukemia; pleura effusion; retinoic acid; lung infiltrate; acute disease; respiratory insufficiency; weight gain; respiratory distress; tretinoin; pleural effusion; human; male; priority journal
Journal Title: New England Journal of Medicine
Volume: 330
Issue: 2
ISSN: 0028-4793
Publisher: Massachusetts Medical Society  
Date Published: 1994-01-13
Start Page: 141
Language: English
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027741156&doi=10.1056%2fNEJM199401133300213&partnerID=40&md5=e072c516dfcc340b51cd5916940c0ee0
Notes: For full correspondence, see DOI: 10.1056/NEJM199401133300213 -- For original article, see PMID: 8515790, DOI: 10.1056/NEJM199307153290307 -- Source: Scopus
MSK Authors
  1. Raymond P Warrell
    175 Warrell
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