Outcomes of low-grade appendiceal mucinous neoplasms with remote acellular mucinous peritoneal deposits Journal Article
| Authors: | Roxburgh, C. S.; Fenig, Y. M.; Cercek, A.; Shia, J.; Rassam, R. M.; Paty, P. B.; Nash, G. M. |
| Article Title: | Outcomes of low-grade appendiceal mucinous neoplasms with remote acellular mucinous peritoneal deposits |
| Abstract: | Background: Occasionally, low-grade appendiceal mucinous neoplasms (LAMN) present with mucinous peritoneal deposits (MPD) localized to periappendiceal tissue or diffused throughout the peritoneum. Objective: This study was aimed at evaluating the relevance of mucin cellularity for predicting outcomes of LAMN with remote MPD. Methods: The records of patients with LAMN and remote MPD who underwent initial assessment at a comprehensive cancer center from 1990 to 2015 were reviewed, and diagnostic procedures, treatments, and outcomes were analyzed. Results: Of 48 patients included in the analysis, 19 had cellular MPD (CMPD) and 29 had acellular MPD. Of 33 patients who underwent cytoreductive surgery, 30 had a complete cytoreduction; the 3 patients with an incomplete cytoreduction had CMPD. In the follow-up period (median, 4 years), 6 patients died of the disease, all of whom had CMPD. Of 11 patients who had progression of disease, 10 had CMPD. Conclusion: Cellularity of remote MPD is an important determinant of disease outcome in LAMN. Approaches such as active surveillance may have a role in selected patients with LAMN and AMPD. © 2018, Society of Surgical Oncology. |
| Journal Title: | Annals of Surgical Oncology |
| Volume: | 26 |
| Issue: | 1 |
| ISSN: | 1068-9265 |
| Publisher: | Springer |
| Date Published: | 2019-01-01 |
| Start Page: | 118 |
| End Page: | 124 |
| Language: | English |
| DOI: | 10.1245/s10434-018-7003-7 |
| PUBMED: | 30421044 |
| PROVIDER: | scopus |
| PMCID: | PMC6339600 |
| DOI/URL: | |
| Notes: | Export Date: 1 February 2019 -- Source: Scopus |
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