Management of locally advanced breast cancer Journal Article


Author: Borgen, P. I.
Article Title: Management of locally advanced breast cancer
Abstract: The management of locally advanced breast cancer with single modality therapy has been associated with a high rate of systemic failure. A multimodality treatment strategy that includes induction cytotoxic chemotherapy, surgery, radiation therapy, and, possibly, hormonal ablation therapy is the current preferred management approach. As our knowledge and understanding of the mechanisms involved in mitogenic signal transduction improve, it is likely that less toxic, more effications agents will emerge. © 1994 Société Internationale de Chirurgie.
Keywords: signal transduction; cancer survival; review; doxorubicin; fluorouracil; advanced cancer; multimodality cancer therapy; antineoplastic agents; cancer radiotherapy; combined modality therapy; methotrexate; breast cancer; cyclophosphamide; breast neoplasms; cancer hormone therapy; randomized controlled trials; breast surgery; clinical trials; history of medicine; human; female; support, non-u.s. gov't
Journal Title: World Journal of Surgery
Volume: 18
Issue: 1
ISSN: 0364-2313
Publisher: Springer  
Date Published: 1994-01-01
Start Page: 81
End Page: 86
Language: English
DOI: 10.1007/bf00348196
PROVIDER: scopus
PUBMED: 8197781
DOI/URL:
Notes: World J. Surg. -- Cited By :6 -- Export Date: 14 January 2019 -- Article -- CODEN: WJSUD C2 - 8197781 -- Source: Scopus
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  1. Patrick I Borgen
    253 Borgen