Author: | Sklar, C. A. |
Title: | Craniopharyngioma: Endocrine abnormalities at presentation |
Conference Title: | Craniopharyngioma: The Answer - Symposium |
Abstract: | Craniopharyngioma is the most common childhood tumor to involve the hypothalamus and pituitary. Although endocrine disturbances can be found in 80-90% of patients at presentation, only a minority of subjects seek medical attention for an endocrine-related complaint. Hormonal studies, while limited, indicate GH deficiency in 75% of children; deficiencies of LH/FSH (40%), ACTH (25%) and TSH (25%) also are common, in contrast, diabetes insipidus has been noted in only 9-17% of subjects prior to surgery. When possible, full evaluation of pituitary function should be performed; the minimum preoperative evaluation must include testing for and treatment of ACTH-adrenal insuffuciency and diabetes insipidus. © 1994 S. Karger AG, Basel. |
Keywords: | child; conference paper; incidence; growth hormone; craniopharyngioma; endocrine disease; thyrotropin; follitropin; luteinizing hormone; corticotropin; pituitary hormones; pituitary gland; diabetes insipidus; pituitary neoplasms; hormone deficiency; human; priority journal; hypophysis function; adrenal gland hypofunction; neoplastic endocrine-like syndromes; pituitary function tests |
Journal Title | Pediatric Neurosurgery |
Volume: | 21 |
Issue: | Suppl. 1 |
Conference Dates: | 1993 Dec 17-19 |
Conference Location: | New York, NY |
ISBN: | 1016-2291 |
Publisher: | Karger |
Date Published: | 1994-01-01 |
Start Page: | 18 |
End Page: | 20 |
Language: | English |
DOI: | 10.1159/000120856 |
PROVIDER: | scopus |
PUBMED: | 7841073 |
DOI/URL: | |
Notes: | (ISBN: 978-3-8055-6048-1) -- Export Date: 14 January 2019 -- Article -- Source: Scopus |