Nutritional vitamin B(12) deficiency in a breastfed infant following maternal gastric bypass Journal Article


Authors: Grange, D. K.; Finlay, J. L.
Article Title: Nutritional vitamin B(12) deficiency in a breastfed infant following maternal gastric bypass
Abstract: Breasfed infants of women who have had gastric or intestinal bypass procedures may develop nutritional deficiencies. We describe a 10-month-old exclusively breastfed white male infant who presented with vomiting, failure to thrive, and megaloblastic anemia. He was found to have vitamin B12 deficiency. His mother had undergone a gastric bypass procedure for morbid obesity 2 years Prior to her pregnancy with this child. She had subclinical vitamin B12 deficiency, with an abnormal Schilling test that corrected with the addition of intrinsic factor. Therefore, we believe that the mother's gastric bypass had caused a decrease in available intrinsic factor, resulting in subclinical vitamin B12 deficiency and decreased breast milk B12. Although she was asymptomatic, her breastfed infant developed symptomatic B12 deficiency. This is the first reported case of a maternal gastric bypass resulting in vitamin B12 deficiency in an infant. These mothers should receive vitamin supplements, including vitamin B12 during and after pregnancy, and my require parenterally administered vitamin B12. © 1994 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
Keywords: adult; clinical feature; case report; vomiting; diet supplementation; chemistry; infant; reference values; pregnancy; cyanocobalamin deficiency; malabsorption; stomach; cyanocobalamin; vitamin b 12; reference value; vitamin b 12 deficiency; morbid obesity; failure to thrive; obesity, morbid; breast feeding; stomach bypass; megaloblastic anemia; breastfeeding; gastric bypass; human; male; female; article; milk, human; breast milk; anemia, megaloblastic
Journal Title: Pediatric Hematology and Oncology
Volume: 11
Issue: 3
ISSN: 0888-0018
Publisher: Taylor & Francis Group  
Date Published: 1994-01-01
Start Page: 311
End Page: 318
Language: English
DOI: 10.3109/08880019409141674
PROVIDER: scopus
PUBMED: 8060815
DOI/URL:
Notes: CODEN: PHONE -- Source: Scopus
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  1. Jonathan Finlay
    67 Finlay