Gallium-67-citrate imaging in nuclear oncology Journal Article


Authors: Macapinlac, H. A.; Scott, A. M.; Larson, S. M.; Divgi, C. R.; Yeh, S. D. J.; Goldsmith, S. J.
Article Title: Gallium-67-citrate imaging in nuclear oncology
Abstract: Gallium-67-citrate is one of the most useful radiopharmaceuticals to detect tumors, stage extent of the disease, monitor response to treatment and distinguish recurrent disease from post-treatment changes. Gallium is likewise very sensitive to detect and locate infections and inflammatory foci. This application is extremely important in the management of immunocompromised cancer patients. Image interpretation should be tempered with full knowledge of the patients clinical condition, anatomic alterations due to prior surgery and correct timing of image acquisition. Early imaging at 4-6 h is useful to detect gastrointestinal infections, whereas 24 h imaging is used to evaluate chest infections. Although gallium-67 is a non-specific agent, the identification of the etiology of the inflammation may be improved by adequate clinical and laboratory information as well as correlation with other imaging modalities such as sonography and computerized x-ray tomography (CT). High dose (10mCi) gallium-67 single photon emission computed tomography (SPECT) imaging with image co-registration is important for accurate uptake localization. © 1994.
Keywords: adult; child; clinical article; conference paper; magnetic resonance imaging; neoplasms; infection; tomography, x-ray computed; immunosuppressive treatment; gallium citrate ga 67; single photon emission computer tomography; cancer scintiscanning; intravenous drug administration; tomography, emission-computed, single-photon; technetium sulfur colloid tc 99m; gallium; hexamethylpropylene amine oxime technetium tc 99m; citrates; gallium radioisotopes; human; male; female
Journal Title: Nuclear Medicine and Biology
Volume: 21
Issue: 5
ISSN: 0969-8051
Publisher: Elsevier Science Inc.  
Date Published: 1994-07-01
Start Page: 731
End Page: 738
Language: English
DOI: 10.1016/0969-8051(94)90044-2
PROVIDER: scopus
PUBMED: 9241649
DOI/URL:
Notes: Export Date: 14 January 2019 -- Article -- CODEN: NMBIE C2 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Samuel D J Yeh
    107 Yeh
  2. Chaitanya Divgi
    163 Divgi
  3. Steven M Larson
    958 Larson
  4. Andrew M. Scott
    62 Scott