Infrared laser Doppler flowmeter in the determination of small bowel perfusion after ischemic injury: Comparison with the clearance of locally generated hydrogen and fluorescein angiography Journal Article

  

Authors:	DiResta, G. R.; Corbally, M. T.; Sigurdson, E. R.; Haumschild, D.; Ridge, R.; Brennan, M. F.
Article Title:	Infrared laser Doppler flowmeter in the determination of small bowel perfusion after ischemic injury: Comparison with the clearance of locally generated hydrogen and fluorescein angiography
Abstract:	The determination of small bowel perfusion after an ischemic insult is difficult. Regional perfusion was determined in an animal model of neonatal intestinal ischemia using the techniques of laser Doppler flowmetry and the clearance of locally generated hydrogen. Both methods reliably measured tissue perfusion in the areas of maximal ischemic injury. However, considerable variability, perhaps owing to motion artifact, was seen in areas of patchy necrosis. The results suggest that the laser Doppler flowmeter is a suitable technique to measure tissue perfusion in areas of maximal ischemia. However, efforts to reduce motion artifact will be necessary if the laser Doppler is to be used in tissue sites where blood flow is critical for safe anastomosis. This will be a subject of future study. © 1994.
Keywords:	controlled study; nonhuman; comparative study; linear models; animal; animal tissue; animal experiment; animal model; ischemia; newborn; intermethod comparison; evaluation studies; small intestine; intestine, small; artifact reduction; fluorescein; hydrogen; fluorescein angiography; rabbits; rabbit; intestine perfusion; laser-doppler flowmetry; intestine necrosis; male; priority journal; article; fluorescence angiography; support, u.s. gov't, p.h.s.; support, u.s. gov't, non-p.h.s.; intestine ischemia; intestinal ischemia, neonatal; small bowel perfusion; hydrogen clearance; laser doppler flowmetry
Journal Title:	Journal of Pediatric Surgery
Volume:	29
Issue:	10
ISSN:	0022-3468
Publisher:	W.B. Saunders Co-Elsevier Inc.
Date Published:	1994-10-01
Start Page:	1352
End Page:	1355
Language:	English
DOI:	10.1016/0022-3468(94)90114-7
PROVIDER:	scopus
PUBMED:	7807324
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028077518&doi=10.1016%2f0022-3468%2894%2990114-7&partnerID=40&md5=28e9b30fb7360e5e49a7a61e7544c067
Notes:	Export Date: 14 January 2019 -- Article -- CODEN: JPDSA C2 -- Source: Scopus

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