The effects of tamoxifen on the endometrium Book Section
| Author: | Barakat, R. R. |
| Editors: | Coukos, G.; Rubin, S. C. |
| Article/Chapter Title: | The effects of tamoxifen on the endometrium |
| Abstract: | Tamoxifen, a nonsteroidal antiestrogen, was first approved by the Food and Drug Administration for the treatment of patients with breast cancer in 1978. Large clinical trials involving over 75,000 patients have demonstrated an improved recurrence-free and overall survival benefit in both pre-and postmenopausal women. Long-term adjuvant tamoxifen is the endocrine treatment of choice for selected patients with breast cancer, and there are currently large-scale trials to evaluate its role as a chemopreventative agent in healthy women at risk for breast cancer. One of the most significant complications of long-term tamoxifen use is the possible development of endometrial cancer. © 2005 by Marcel Dekker. All rights reserved. |
| Book Title: | Cancer of the Uterus |
| ISBN: | 0824754158 |
| Publisher: | Marcel Dekker, Inc. |
| Publication Place: | New York, NY |
| Date Published: | 2005-01-01 |
| Start Page: | 79 |
| End Page: | 92 |
| Language: | English |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 4 -- Source: Scopus |
MSK Authors
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629Barakat
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