Targeting the insulin-like growth factor pathway in estrogen receptor-positive breast cancer: A bumpy start with an uncertain future Journal Article


Author: Dickler, M. N.
Article Title: Targeting the insulin-like growth factor pathway in estrogen receptor-positive breast cancer: A bumpy start with an uncertain future
Keywords: mitogen activated protein kinase; protein kinase b; somatomedin; cancer survival; protein phosphorylation; treatment response; unclassified drug; overall survival; drug tolerability; placebo; cancer combination chemotherapy; cancer risk; diarrhea; adjuvant therapy; cancer adjuvant therapy; disease free survival; antineoplastic agent; adenocarcinoma; cell proliferation; metastasis; progression free survival; apoptosis; breast cancer; antineoplastic combined chemotherapy protocols; epidermal growth factor receptor 2; somatomedin binding protein 1; editorial; antineoplastic activity; breast neoplasms; phosphatidylinositol 3 kinase; exemestane; somatomedin c receptor; cancer hormone therapy; cancer cell; tamoxifen; insulin; cancer relapse; inhibition kinetics; octreotide; letrozole; somatomedin c; antineoplastic agents, hormonal; estrogen receptor; trastuzumab; cholecystectomy; anastrozole; postmenopause; metformin; non insulin dependent diabetes mellitus; ligand binding; lapatinib; gallbladder disease; somatomedin b; somatomedin binding protein 6; fulvestrant; intracellular signaling; hormone blood level; insulin receptor; randomized controlled trial (topic); molecularly targeted therapy; receptor upregulation; phase 2 clinical trial (topic); phase 3 clinical trial (topic); hyperinsulinemia; gluconeogenesis; ganitumab; 25 hydroxyvitamin d; c peptide; bms 754807; estrogen receptor positive breast cancer; gastrointestinal pain
Journal Title: Journal of Clinical Oncology
Volume: 29
Issue: 29
ISSN: 0732-183X
Publisher: American Society of Clinical Oncology  
Date Published: 2011-10-10
Start Page: 3846
End Page: 3848
Language: English
DOI: 10.1200/jco.2011.36.6393
PROVIDER: scopus
PUBMED: 21911731
DOI/URL:
Notes: --- - "Export Date: 2 November 2011" - "CODEN: JCOND" - "Source: Scopus"
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  1. Maura N Dickler
    262 Dickler