Chromosomal abnormalities in choriocarcinomas of the female Journal Article


Authors: Rodriguez, E.; Melamed, J.; Reuter, V.; Chaganti, R. S. K.
Article Title: Chromosomal abnormalities in choriocarcinomas of the female
Abstract: We have studied six cases of choriocarcinomas in the female by conventional cytogenetic analysis and by in situ hybridization using a 12p painting probe, and found evidence for chromosome 12 abnormalities in two of them. Abnormalities of chromosome 12 are a common occurrence in genitourinary tumors of the female, but their significance is not known. We discuss the present findings in relation to those in malignant ovarian germ cell tumors (MOGCTs).
Keywords: cytogenetic analysis; hybridization; lines; origin; trisomy-12; stromal cell tumors
Journal Title: Cancer Genetics and Cytogenetics
Volume: 80
Issue: 1
ISSN: 0165-4608
Publisher: Elsevier Science, Inc.  
Date Published: 1995-03-01
Start Page: 9
End Page: 12
Language: English
ACCESSION: WOS:A1995QQ23000002
DOI: 10.1016/0165-4608(94)00145-2
PROVIDER: wos
PUBMED: 7697645
Notes: Article -- Source: Wos
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  1. Victor Reuter
    1227 Reuter
  2. Raju S K Chaganti
    391 Chaganti
  3. Jonathan Melamed
    22 Melamed