Stereotactic body radiotherapy with functional treatment planning in hepatocellular carcinoma Journal Article


Authors: Kirichenko, A.; Koay, E. J.; Hasan, S.; Crane, C.
Article Title: Stereotactic body radiotherapy with functional treatment planning in hepatocellular carcinoma
Abstract: Hepatocellular carcinoma (HCC) is the fastest growing cause of cancer-related death in the United States, and considered an aggressive tumor with mean survival estimated between 6 and 20 months (El-Serag, NEJM 365:1118–1127, 2011). The choice of curative liver resection is limited by the presence of hepatic cirrhosis in 90% of patients, and the most appropriate therapy for HCC has historically been hepatic transplantation with 5-year survival rate of up to 85%. However, only 10% of patients are eligible for surgery (Fortune et al., J Clin Gastroenterol 47:S37–S42, 2013). We discuss functional treatment planning for patients with hepatic cirrhosis and HCC and present an argument in favor of liver SBRT as a viable option. © Springer International Publishing AG.
Journal Title: Medical Radiology
ISSN: 0942-5373
Publisher: Springer Nature  
Date Published: 2018-01-01
Start Page: 203
End Page: 210
Language: English
DOI: 10.1007/174_2017_42
PROVIDER: scopus
DOI/URL:
Notes: Book Chapter in "Alternate Fractionation in Radiotherapy: Paradigm Change" (ISBN: 978-3-319-51197-9), which is part of a subseries of Medical Radiology called "Radiation Oncology" (ISSN: 2731-4715) -- Export Date: 1 November 2018 -- Source: Scopus
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  1. Christopher   Crane
    166 Crane