Abstract: |
A Swedish neurosurgeon and scientist, Lars Leksell (1907-1986) at the age of 42, designed and developed the world’s first stereotactic frame based on three-dimensional Cartesian coordinate system [1,2]. Two years later in 1951, Leksell and a medical physicist named Borje Larsson developed the earliest methodology of radiosurgery by using X-ray beams generated from the Uppsala University cyclotron [3]. Their goal was to treat small intracranial tumors that were not accessible by conventional surgery noninvasively. The initial concept of radiosurgery was to deliver a series of slit beams of radiation from multiple directions and focus them on the target. In this way, the target can receive a lethal dose of radiation, whereas the nearby healthy tissue can be adequately spared. © 2018 by Taylor and Francis Group, LLC. |