Bone marrow transplantation versus chemotherapy in non-Hodgkin's lymphoma Journal Article


Authors: Nimer, S. D.; Zelenetz, A.; Portlock, C.
Article Title: Bone marrow transplantation versus chemotherapy in non-Hodgkin's lymphoma
Abstract: To the Editor: In their study of the efficacy of high-dose chemotherapy and autologous bone marrow transplantation in patients with non-Hodgkin's lymphoma who respond slowly to chemotherapy, Verdonck et al. (April 20 issue)1 used response criteria that may have influenced the outcome. A variety of criteria have been proposed to assess response in patients with lymphoma, but the most widely accepted are those ratified at the Cotswolds meeting,2 which define a partial remission as “a decrease by at least 50 percent in the sum of the products of the largest perpendicular diameters of all measurable lesions.” In contrast, Verdonck et. © 1995, Massachusetts Medical Society. All rights reserved.
Keywords: cancer survival; treatment outcome; prednisone; doxorubicin; cancer combination chemotherapy; dose response; drug efficacy; multimodality cancer therapy; note; combined modality therapy; antineoplastic agent; letter; classification; tumor volume; antineoplastic combined chemotherapy protocols; cyclophosphamide; vincristine; cancer regression; nonhodgkin lymphoma; statistical analysis; data interpretation, statistical; lymphoma, non-hodgkin; remission; remission induction; bone marrow transplantation; autologous bone marrow transplantation; human; priority journal
Journal Title: New England Journal of Medicine
Volume: 333
Issue: 11
ISSN: 0028-4793
Publisher: Massachusetts Medical Society  
Date Published: 1995-09-14
Start Page: 728
End Page: 729
Language: English
DOI: 10.1056/nejm199509143331111
PUBMED: 7503899
PROVIDER: scopus
DOI/URL:
Notes: Letter -- Export Date: 28 August 2018 -- Source: Scopus
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  1. Carol Portlock
    206 Portlock
  2. Andrew D Zelenetz
    781 Zelenetz
  3. Stephen D Nimer
    347 Nimer