Memorial Sloan-Kettering Cancer Center experience with paclitaxel in the treatment of breast cancer Conference Paper
| Authors: | Seidman, A. D.; Hudis, C. A.; Fennelly, D.; Raptis, G.; Baselga, J.; Norton, L. |
| Title: | Memorial Sloan-Kettering Cancer Center experience with paclitaxel in the treatment of breast cancer |
| Conference Title: | The Fox Chase Cancer Center Investigators' Workshop and Consensus Conference |
| Abstract: | Paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ) is the most important new cytotoxic agent to be introduced for the management of breast cancer in many years. During this decade, investigators at Memorial Sloan-Kettering Cancer Center have conducted multiple clinical and laboratory investigations aimed at optimally integrating this agent into therapeutic strategies for breast cancer. These studies address both single-agent and combination regimens in the metastatic and adjuvant settings. This report will review previous results, but focus on active studies and future avenues of research. |
| Keywords: | controlled study; clinical trial; fatigue; neutropenia; cisplatin; cytotoxic agent; doxorubicin; cancer combination chemotherapy; diarrhea; drug potentiation; skin toxicity; conference paper; paclitaxel; cancer adjuvant therapy; chemotherapy, adjuvant; methotrexate; cancer staging; lymphatic metastasis; quality of life; controlled clinical trial; phase 2 clinical trial; breast cancer; blood toxicity; nausea; randomized controlled trial; stomatitis; antineoplastic combined chemotherapy protocols; drug administration schedule; antineoplastic agents, phytogenic; cyclophosphamide; bone pain; clinical protocol; antineoplastic activity; breast neoplasms; thiotepa; docetaxel; drug fever; cancer center; randomized controlled trials; tamoxifen; phase 3 clinical trial; phase 1 clinical trial; recombinant granulocyte colony stimulating factor; alopecia; intravenous drug administration; growth substances; edatrexate; subcutaneous drug administration; humans; human; female; priority journal |
| Journal Title | Seminars in Oncology |
| Volume: | 22 |
| Issue: | 5 Suppl. 12 |
| Conference Dates: | 1995 Mar 22-26 |
| Conference Location: | St. John, US Virgin Islands |
| ISBN: | 0093-7754 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1995-10-01 |
| Start Page: | 108 |
| End Page: | 116 |
| Language: | English |
| PUBMED: | 7481852 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Conference Paper -- Export Date: 28 August 2018 -- Source: Scopus |
