An analysis of expenditures on primary care prescription drugs in the United States versus ten comparable countries Journal Article


Authors: Morgan, S. G.; Good, C. B.; Leopold, C.; Kaltenboeck, A.; Bach, P. B.; Wagner, A.
Article Title: An analysis of expenditures on primary care prescription drugs in the United States versus ten comparable countries
Abstract: Objective: We sought to estimate size and sources of differences in per capita expenditures on primary care medications in the US versus ten comparable countries combined: Australia, Canada, France, Germany, the Netherlands, New Zealand, Norway, Sweden, Switzerland, and the United Kingdom. Methods: Using market research data on year 2015 volumes and sales of medicines, we measure total per capita expenditures on six categories of primary care prescription drugs: hypertension treatments, pain medications, lipid lowing medicines, non-insulin diabetes treatments, gastrointestinal preparations, and antidepressants. We quantified the contributions of five drivers of the observed differences in per capita expenditures. Results: We estimated that the US spent 203% more per capita on primary care pharmaceuticals than did the ten comparable countries. Despite the difference in spending levels, on average, Americans actually purchased 12% fewer days of related therapies than residents of the comparator countries. Most of the observed difference in expenditures was due to higher transaction prices of medicines and the use of a more expensive mix of medicines in the US. Conclusions: If utilization patterns and pharmaceutical prices in the US were similar to those in the 10 comparator countries combined, total spending on primary care pharmaceuticals would fall by 30% or more. Such evidence on the level and drivers of US pharmaceutical expenditures should inform policies in this sector. © 2018 Elsevier B.V.
Keywords: controlled study; united states; comparative study; netherlands; sweden; drug cost; narcotic analgesic agent; quantitative analysis; nonsteroid antiinflammatory agent; antidepressant agent; australia; antidiabetic agent; antihypertensive agent; antilipemic agent; drug utilization; canada; dipeptidyl carboxypeptidase inhibitor; ramipril; primary medical care; united kingdom; diuretic agent; germany; france; new zealand; norway; drug choice; economic evaluation; enalapril; prescription drug; prescription drugs; prices; gastrointestinal agent; switzerland; pharmaceuticals; article; cost-drivers; expenditures; international comparisons
Journal Title: Health Policy
Volume: 122
Issue: 9
ISSN: 0168-8510
Publisher: Elsevier Ireland Ltd.  
Date Published: 2018-09-01
Start Page: 1012
End Page: 1017
Language: English
DOI: 10.1016/j.healthpol.2018.07.005
PROVIDER: scopus
PUBMED: 30041827
DOI/URL:
Notes: Article -- Export Date: 5 October 2018 -- Source: Scopus
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  1. Peter Bach
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