Adrenal masses in patients with malignancy: Prospective comparison of echo-planar, fast spin-echo, and chemical shift MR imaging Journal Article

  


Authors: Schwartz, L. H.; Panicek, D. M.; Koutcher, J. A.; Brown, K. T.; Getrajdman, G. I.; Heelan, R. T.; Burt, M.
Article Title: Adrenal masses in patients with malignancy: Prospective comparison of echo-planar, fast spin-echo, and chemical shift MR imaging
Abstract: PURPOSE: To assess echo-planar, fast spin-echo (SE), and chemical shift magnetic resonance (MR) imaging in differentiation of adrenal adenomas from malignant adrenal masses in patients with known malignancy. MATERIALS AND METHODS: Sixty-eight adrenal masses (23 malignant, 45 benign) in 68 patients with known malignancy were examined with echoplanar, fast SE with and without fat suppression, and chemical shift pulse sequences. RESULTS: With a cutoff T2 value of 75 msec, the sensitivity of echo-planar imaging for benign lesions was 82%, and specificity was 96%. With a cutoff adrenal mass-to- spleen signal intensity ratio of 0.80, the sensitivity of fast SE imaging for benign lesions was 53%, and specificity was 96%. With a cutoff adrenal mass- to-spleen ratio of 0.55, the sensitivity of chemical shift imaging for benign lesions was 80%, and specificity was 100%. CONCLUSION: Chemical shift imaging and calculated T2 values from echo-planar imaging are promising techniques for differentiation of adrenal adenomas from malignant adrenal masses and can obviate biopsy.
Keywords: adult; controlled study; aged; major clinical study; nuclear magnetic resonance imaging; diagnostic accuracy; lung cancer; diagnostic imaging; adrenal metastasis; adrenal cancer; human; male; female; priority journal; article; adrenal cortex adenoma; adrenal gland, mr; adrenal gland, neoplasms
Journal Title: Radiology
Volume: 197
Issue: 2
ISSN: 0033-8419
Publisher: Radiological Society of North America, Inc.  
Date Published: 1995-11-01
Start Page: 421
End Page: 425
Language: English
DOI: 10.1148/radiology.197.2.7480686
PUBMED: 7480686
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028875331&doi=10.1148%2fradiology.197.2.7480686&partnerID=40&md5=5cc316146fb033be24d62d47266d906f
Notes: Article -- Export Date: 28 August 2018 -- Source: Scopus
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MSK Authors
  1. David M Panicek
    135 Panicek
  2. George I Getrajdman
    118 Getrajdman
  3. Lawrence H Schwartz
    307 Schwartz
  4. Karen T Brown
    178 Brown
  5. Jason A Koutcher
    278 Koutcher
  6. Robert T Heelan
    140 Heelan
  7. Michael E. Burt
    187 Burt
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