Author: | Straus, D. J. |
Article Title: | Chemotherapy only for localized Hodgkin lymphoma |
Abstract: | Radiation therapy (RT) alone and more recently in combination with chemotherapy (combined modality therapy; CMT) has been the cornerstone of curative treatment for early-stage Hodgkin lymphoma (HL) for over 40years. Because of increasing awareness of the late morbidity and mortality associated with RT, recent treatment regimens have attempted to limit its use. Chemotherapy only has been demonstrated to be a treatment option for most patients with localized HL. Current clinical trials have targeted subgroups of such patients who may be at an increased risk of recurrence for the addition of limited RT to chemotherapy. © 2011 The Association for the Publication of the Journal of Internal Medicine. |
Keywords: | overall survival; prednisone; review; doxorubicin; cancer risk; multimodality cancer therapy; radiation dose; chemotherapy; dacarbazine; progression free survival; lung toxicity; etoposide; morbidity; cyclophosphamide; vincristine; cancer mortality; procarbazine; hodgkin disease; bleomycin; awareness; localized hodgkin lymphoma |
Journal Title: | Journal of Internal Medicine |
Volume: | 270 |
Issue: | 3 |
ISSN: | 0954-6820 |
Publisher: | Wiley Blackwell |
Date Published: | 2011-09-01 |
Start Page: | 197 |
End Page: | 205 |
Language: | English |
DOI: | 10.1111/j.1365-2796.2011.02410.x |
PROVIDER: | scopus |
PUBMED: | 21668822 |
DOI/URL: | |
Notes: | --- - "Export Date: 3 October 2011" - "CODEN: JINME" - "Source: Scopus" |