Prevention of Clostridium difficile-toxin-associated diarrhea in patients with neoplastic disease Journal Article
| Authors: | Eagan, J. A.; Brown, A. E. |
| Article Title: | Prevention of Clostridium difficile-toxin-associated diarrhea in patients with neoplastic disease |
| Abstract: | The toxin produced by Clostridium difficile is a major cause of nosocomial diarrhea. Antibiotic use predisposes patients to C. difficile acquisition and overgrowth. Patients with neoplastic disease are at increased risk because of additional factors including chemotherapy, surgery, and debilitation. Transmission in the hospital setting occurs via hand carriage by health care workers and by environmental contamination. Measures to reduce transmission include hand washing, isolation, barrier garb use, and environmental disinfection. Early diagnosis will lead to initiation of preventive measures that will subsequently decrease transmission of this nosocomial pathogen. |
| Keywords: | antibiotic agent; neutropenia; doxorubicin; fluorouracil; diarrhea; methotrexate; antineoplastic agent; cyclophosphamide; risk factor; clostridium difficile; contamination; bacterial growth; disinfection; cancer; human; article; hypochlorite sodium |
| Journal Title: | Infections in Medicine |
| Volume: | 12 |
| Issue: | 12 |
| ISSN: | 0749-6524 |
| Publisher: | SCP Communications |
| Date Published: | 1995-12-01 |
| Start Page: | 678, 687, 690 |
| Language: | English |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 28 August 2018 -- Source: Scopus |
