Contemporary management of sinonasal cancer Journal Article
| Authors: | Robbins, K. T.; Ferlito, A.; Silver, C. E.; Takes, R. P.; Strojan, P.; Snyderman, C. H.; De Bree, R.; Haigentz, M. Jr; Langendijk, J. A.; Rinaldo, A.; Shaha, A. R.; Hanna, E. Y.; Werner, J. A.; Suárez, C. |
| Article Title: | Contemporary management of sinonasal cancer |
| Abstract: | Background. Sinonasal cancer is a relatively uncommon entity encountered by head and neck oncologists, rhinologists, and skull base surgeons. Recent innovations in surgical and nonsurgical therapeutic modalities raise the question of whether there has been any measurable improvement for treatment outcomes. Methods. A retrospective review of data from recent studies that focus on surgery, radiation, and chemotherapy, or combinations thereof, was conducted. Results. Surgery continues to be the preferred treatment and provides the best results, albeit with an inherent bias based on patient selection. For advanced disease (T4 lesions), the survival rate remains only modest. Complications of treatment, including both surgical and radiation therapy, have been reduced. Conclusions. There is a need to improve the efficacy of treatment for this disease. Recommendations for the future direction of therapeutic investigations are outlined. © 2010 Wiley Periodicals, Inc. Head Neck, 2010 Copyright © 2010 Wiley Periodicals, Inc. |
| Keywords: | cancer chemotherapy; cancer survival; treatment outcome; cancer surgery; graft infection; overall survival; hydroxyurea; clinical feature; review; cancer recurrence; intensity modulated radiation therapy; cisplatin; fluorouracil; advanced cancer; multimodality cancer therapy; cancer radiotherapy; disease free survival; postoperative care; radiation dose; chemotherapy; treatment; cancer staging; nuclear magnetic resonance imaging; follow up; undifferentiated carcinoma; imatinib; stem cell factor receptor; vasculotropin receptor; quality of life; computer assisted tomography; epidermal growth factor receptor; cetuximab; neuroendocrine tumor; postoperative complication; cancer invasion; graft failure; systematic review; radiation dose fractionation; conservative treatment; postoperative infection; surgical mortality; cancer relapse; retinopathy; radiation therapy; therapy effect; adenoid cystic carcinoma; disease control; computer assisted radiotherapy; paranasal sinus cancer; blindness; craniofacial surgery; meningitis; esthesioneuroblastoma; brain hemorrhage; bone necrosis; topical treatment; radiation necrosis; chemoradiotherapy; cause specific survival; jaw osteonecrosis; hypopituitarism; radical resection; endoscopic surgical resection; sinonasal cancer; bilateral blindness; cerebrospinal fluid otorrhea; endoscopic sinus surgery; ipsilateral blindness; neovascular glaucoma; radiation induced retinopathy; topical chemotherapy |
| Journal Title: | Head & Neck |
| Volume: | 33 |
| Issue: | 9 |
| ISSN: | 1043-3074 |
| Publisher: | John Wiley & Sons, Inc. |
| Date Published: | 2011-09-01 |
| Start Page: | 1352 |
| End Page: | 1365 |
| Language: | English |
| DOI: | 10.1002/hed.21515 |
| PROVIDER: | scopus |
| PUBMED: | 20737500 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 3 October 2011" - "CODEN: HEANE" - "Source: Scopus" |
