Quality of life concerns and depression among hematopoietic stem cell transplant survivors Journal Article
| Authors: | Mosher, C. E.; Duhamel, K. N.; Rini, C.; Corner, G.; Lam, J.; Redd, W. H. |
| Article Title: | Quality of life concerns and depression among hematopoietic stem cell transplant survivors |
| Abstract: | Purpose: This study examined quality of life, transplant-related concerns, and depressive symptoms and their demographic and medical correlates at 1 to 3 years following hematopoietic stem cell transplantation (HSCT). Methods: HSCT survivors (N=406) completed telephone-administered questionnaires that assessed demographic variables, functional status, quality of life, transplant-related concerns, and depressive symptoms. Results: The most prevalent concerns among HSCT survivors included physical symptoms (e.g., fatigue and pain), maintaining current health status and employment, changes in appearance, and lack of sexual interest and satisfaction. In addition, almost one-third (32%) of survivors age 40 years and younger reported concern about their ability to have children. Unemployed survivors and those with lower incomes and worse functional status were more likely to experience poorer quality of life in multiple domains. Fifteen percent of the sample reported moderate to severe depressive symptoms, and these symptoms were higher among allogeneic transplant recipients and those with lower functional status. Conclusions: Results suggest that interventions are needed to address physical symptoms, coping with an uncertain future, infertility, and sexual issues during the early phase of HSCT survivorship. © 2010 Springer-Verlag. |
| Keywords: | adult; middle aged; patient satisfaction; functional assessment; transplantation, homologous; major clinical study; neoplasms; quality of life; prevalence; cancer pain; hematopoietic stem cell transplantation; infertility; age; cancer survivor; questionnaires; survivors; depression; symptom; disease severity; health status; karnofsky performance status; severity of illness index; cancer fatigue; allogeneic hematopoietic stem cell transplantation; attitude to illness; cross-sectional studies; sex difference; educational status; marriage; family relation; transplantation, autologous; functional status; autologous hematopoietic stem cell transplantation; sexual behavior; income; decreased appetite; employment; cancer survivorship; unemployment; psychological; sexual health; friend; beck depression inventory; childlessness |
| Journal Title: | Supportive Care in Cancer |
| Volume: | 19 |
| Issue: | 9 |
| ISSN: | 0941-4355 |
| Publisher: | Springer Verlag |
| Date Published: | 2011-09-01 |
| Start Page: | 1357 |
| End Page: | 1365 |
| Language: | English |
| DOI: | 10.1007/s00520-010-0958-y |
| PROVIDER: | scopus |
| PUBMED: | 20661753 |
| PMCID: | PMC3760694 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 3 October 2011" - "CODEN: SCCAE" - "Source: Scopus" |
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