A TeNaCious Foundation for the Metastatic Niche Journal Article
| Authors: | Matei, I.; Ghajar, C.; Lyden, D. |
| Article Title: | A TeNaCious Foundation for the Metastatic Niche |
| Abstract: | In the July issue of Nature Medicine, Massagué and colleagues define a biphasic role for the extracellular matrix protein tenascin C as a metastatic niche component in lung colonization by breast cancer cells. These results provide a rationale for designing therapies targeting metastatic progression by disrupting its very foundations. © 2011 Elsevier Inc. |
| Keywords: | signal transduction; protein expression; protein domain; protein function; cell proliferation; cell survival; metastasis; protein protein interaction; notch receptor; scleroprotein; extracellular matrix; lung metastasis; cancer cell; micrometastasis; short survey; tumor growth; protein structure; wnt protein; breast cell; pleiotropy; cell homing; cell surface protein; tissue specificity; syndecan 4; tenascin |
| Journal Title: | Cancer Cell |
| Volume: | 20 |
| Issue: | 2 |
| ISSN: | 1535-6108 |
| Publisher: | Cell Press |
| Date Published: | 2011-01-01 |
| Start Page: | 139 |
| End Page: | 141 |
| Language: | English |
| DOI: | 10.1016/j.ccr.2011.08.004 |
| PROVIDER: | scopus |
| PUBMED: | 21840480 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 3 October 2011" - "CODEN: CCAEC" - "Source: Scopus" |
