Investigating the robustness neighborhood gray tone difference matrix and gray level co-occurrence matrix radiomic features on clinical computed tomography systems using anthropomorphic phantoms: Evidence from a multivendor study Journal Article

   

Authors:	Mahmood, U.; Apte, A. P.; Deasy, J. O.; Schmidtlein, C. R.; Shukla-Dave, A.
Article Title:	Investigating the robustness neighborhood gray tone difference matrix and gray level co-occurrence matrix radiomic features on clinical computed tomography systems using anthropomorphic phantoms: Evidence from a multivendor study
Abstract:	Objective: The aim of this study was to determine if optimized imaging protocols across multiple computed tomography (CT) vendors could result in reproducible radiomic features calculated from an anthropomorphic phantom. Methods: Materials with varying degrees of heterogeneity were placed throughout the lungs of the phantom. Twenty scans of the phantom were acquired on 3 CT manufacturers with chest CT protocols that had optimized protocol parameters. Scans were reconstructed using vendor-specific standards and lung kernels. The concordance correlation coefficient (CCC) was used to calculate reproducibility between features. For features with high CCC values, Bland-Altman analysis was also used to quantify agreement. Results: Themean Hounsfield unit (HU)was 32.93HU(141.7 to -26.5 HU) for the rubber insert and 347.2 HU (-320.9 to -347.7 HU) for the wood insert. Low CCC values of less than 0.9 were calculated for all features across all scans. Conclusions: Radiomic features that are derived from the spatial distribution of voxel intensities should be particularly scrutinized for reproducibility in a multivendor environment. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.
Keywords:	comparative study; reproducibility; reproducibility of results; tomography, x-ray computed; lung; phantoms, imaging; computed tomography; computed tomography scanner; tomography scanners, x-ray computed; imaging phantom; humans; human; anthropomorphic phantom; x-ray computed tomography; radiomics
Journal Title:	Journal of Computer Assisted Tomography
Volume:	41
Issue:	6
ISSN:	0363-8715
Publisher:	Lippincott Williams & Wilkins
Date Published:	2017-11-01
Start Page:	995
End Page:	1001
Language:	English
DOI:	10.1097/rct.0000000000000632
PUBMED:	28708732
PROVIDER:	scopus
PMCID:	PMC5685887
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85023757699&doi=10.1097%2fRCT.0000000000000632&partnerID=40&md5=08d56e73bd14fc623c3801390e9e945b
Notes:	Article -- Export Date: 4 September 2018 -- Source: Scopus

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