Enhancing decision making about participation in cancer clinical trials: Development of a question prompt list Journal Article
| Authors: | Brown, R. F.; Shuk, E.; Leighl, N.; Butow, P.; Ostroff, J.; Edgerson, S.; Tattersall, M. |
| Article Title: | Enhancing decision making about participation in cancer clinical trials: Development of a question prompt list |
| Abstract: | Purpose: Slow accrual to cancer clinical trials impedes the progress of effective new cancer treatments. Poor physician-patient communication has been identified as a key contributor to low trial accrual. Question prompt lists (QPLs) have demonstrated a significant promise in facilitating communication in general, surgical, and palliative oncology settings. These simple patient interventions have not been tested in the oncology clinical trial setting. We aimed to develop a targeted QPL for clinical trials (QPL-CT). Method: Lung, breast, and prostate cancer patients who either had (trial experienced) or had not (trial naive) participated in a clinical trial were invited to join focus groups to help develop and explore the acceptability of a QPL-CT. Focus groups were audio-recorded and transcribed. A research team, including a qualitative data expert, analyzed these data to explore patients' decision-making processes and views about the utility of the QPL-CT prompt to aid in trial decision making. Results: Decision making was influenced by the outcome of patients' comparative assessment of perceived risks versus benefits of a trial, and the level of trust patients had in their doctors' recommendation about the trial. Severity of a patient's disease influenced trial decision making only for trial-naive patients. Conclusion: Although patients were likely to prefer a paternalistic decision-making style, they expressed valuation of the QPL as an aid to decision making. QPL-CT utility extended beyond the actual consultation to include roles both before and after the clinical trial discussion. © 2010 Springer-Verlag. |
| Keywords: | adult; clinical article; controlled study; aged; risk benefit analysis; cancer patient; cancer staging; outcome assessment; tumor localization; breast cancer; lung cancer; information processing; urogenital tract cancer; risk factor; prostate cancer; questionnaire; intervention study; patient participation; disease severity; doctor patient relation; education; consultation; marriage; decision making; clinical trials; qualitative analysis; clinical trial (topic); trust; physician-patient communication; audio recording; question prompt lists; question prompt list |
| Journal Title: | Supportive Care in Cancer |
| Volume: | 19 |
| Issue: | 8 |
| ISSN: | 0941-4355 |
| Publisher: | Springer Verlag |
| Date Published: | 2011-08-01 |
| Start Page: | 1227 |
| End Page: | 1238 |
| Language: | English |
| DOI: | 10.1007/s00520-010-0942-6 |
| PROVIDER: | scopus |
| PUBMED: | 20593202 |
| PMCID: | PMC4834985 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 3 October 2011" - "CODEN: SCCAE" - "Source: Scopus" |
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