Electronic toxicity monitoring and patient-reported outcomes Journal Article
| Authors: | Basch, E. M.; Reeve, B. B.; Mitchell, S. A.; Clauser, S. B.; Minasian, L.; Sit, L.; Chilukuri, R.; Baumgartner, P.; Rogak, L.; Blauel, E.; Abernethy, A. P.; Bruner, D. |
| Article Title: | Electronic toxicity monitoring and patient-reported outcomes |
| Abstract: | Understanding the potential profile of adverse events associated with cancer treatment is essential in balancing safety versus benefits. Multiple stakeholders make use of this information for decision making, including patients, clinicians, researchers, regulators, and payors. Currently, adverse events are reported by clinical research staff, yet evidence suggests that this may contribute to underreporting of symptom events. Direct patient reporting via electronic interfaces offers a promising mechanism to enhance the efficiency and precision of our current approach and may complement clinician reports of adverse events. The National Cancer Institute has contracted to develop and test an item bank and software system for directly eliciting adverse symptom event information from patients in cancer clinical research, called the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events. The validity, usability, and scalability of the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events prototype are currently being examined in academic and community-based settings. Copyright © 2011 by Lippincott Williams & Wilkins. |
| Keywords: | treatment outcome; review; drug safety; risk benefit analysis; unspecified side effect; antineoplastic agents; outcome assessment; antineoplastic agent; neoplasms; quality of life; breast cancer; computer interface; patient monitoring; practice guideline; information processing; cancer therapy; self report; electronic medical record; symptom; disease severity; health status; patient safety; drug monitoring; asthma; osteoarthritis; drug labeling; toxicity; gastroesophageal reflux; computer program; software; postmarketing surveillance; adverse drug reaction; hyperlipidemia; national health organization; adverse event; computer communication networks; research report; patient-reported outcome; pro; tolerability; ctcae; pro-ctcae; drug information; medical informatics |
| Journal Title: | The Cancer Journal |
| Volume: | 17 |
| Issue: | 4 |
| ISSN: | 1528-9117 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2011-07-01 |
| Start Page: | 231 |
| End Page: | 234 |
| Language: | English |
| DOI: | 10.1097/PPO.0b013e31822c28b3 |
| PROVIDER: | scopus |
| PUBMED: | 21799330 |
| PMCID: | PMC3855320 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 3 October 2011" - "CODEN: CAJOC" - "Source: Scopus" |
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