NK/T-cell lymphoma, nasal type, γδ T-cell lymphoma, and CD8-positive epidermotropic T-cell lymphoma - Clinical and histopathologic features, differential diagnosis, and treatment Journal Article


Authors: Geller, S.; Myskowski, P. L.; Pulitzer, M.
Article Title: NK/T-cell lymphoma, nasal type, γδ T-cell lymphoma, and CD8-positive epidermotropic T-cell lymphoma - Clinical and histopathologic features, differential diagnosis, and treatment
Abstract: The cytotoxic lymphomas of the skin constitute a heterogeneous group of rare lymphoproliferative diseases that are derived from mature T cells and natural killer (NK) cells that express cytotoxic molecules (T-cell intracellular antigen- 1, granzyme A/B, and perforin). Although frequently characterized by an aggressive course and poor prognosis, these diseases can have variable clinical behavior. This review delivers up-to-date information about the clinical presentation, histopathologic features, differential diagnosis, and therapy of extranodal NK/T-cell lymphoma, nasal type, primary cutaneous gamma delta T-cell lymphoma, and primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma. © 2018 Frontline Medical Communications.
Journal Title: Seminars in Cutaneous Medicine and Surgery
Volume: 37
Issue: 1
ISSN: 1085-5629
Publisher: W.B. Saunders Co-Elsevier Inc.  
Date Published: 2018-03-01
Start Page: 30
End Page: 38
Language: English
DOI: 10.12788/j.sder.2018.020
PROVIDER: scopus
PUBMED: 29719018
PMCID: PMC6331058
DOI/URL:
Notes: Article -- Export Date: 1 August 2018 -- Source: Scopus
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  1. Melissa P Pulitzer
    203 Pulitzer
  2. Patricia Myskowski
    216 Myskowski
  3. Shamir Geller
    52 Geller