Surgical management of the axilla: Do intramammary nodes matter? Journal Article


Authors: Pugliese, M. S.; Stempel, M. M.; Cody, H. S. 3rd; Morrow, M.; Gemignani, M. L.
Article Title: Surgical management of the axilla: Do intramammary nodes matter?
Abstract: Background: The therapeutic significance of intramammary lymph nodes is uncertain. The purpose of this study was to identify the appropriate surgical management of the axilla in intramammary node-positive patients undergoing sentinel lymph node (SLN) biopsy. Methods: A retrospective review of consecutive patients staged between September 1996 and December 2004 was performed. Intramammary node identification and pathologic findings were compared with the status of axilla. Results: Among 7,140 patients, intramammary nodes were identified in 151 (2%). Positive intramammary nodes were identified in 36 patients (24%). Axillary disease was identified in 61% of intramammary node-positive patients. No additional axillary disease was identified when axillary lymph node dissection was performed in intramammary node-positive patients with negative axillary SLN biopsy results. Conclusions: The results suggest that completion axillary lymph node dissection may be based on the status of axillary SLN biopsies in clinically node negative patients when intramammary lymph node metastases are identified in the breast specimens. © 2009 Elsevier Inc. All rights reserved.
Keywords: adult; human tissue; middle aged; surgical technique; retrospective studies; major clinical study; histopathology; patient selection; cancer staging; lymph node metastasis; lymph node dissection; lymph nodes; lymphatic metastasis; neoplasm staging; sentinel lymph node; sentinel lymph node biopsy; breast cancer; breast; breast neoplasms; retrospective study; prediction; cancer invasion; axillary lymph node; lymph node; predictive value of tests; axilla; completion axillary lymph node dissection; alnd; axillary lymph node dissection; calnd; intramammary lymph nodes; sln; intramammary lymph node
Journal Title: American Journal of Surgery
Volume: 198
Issue: 4
ISSN: 0002-9610
Publisher: Elsevier Inc.  
Date Published: 2009-10-01
Start Page: 532
End Page: 537
Language: English
DOI: 10.1016/j.amjsurg.2009.06.007
PUBMED: 19800463
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 30 November 2010" - "CODEN: AJSUA" - "Source: Scopus"
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MSK Authors
  1. Monica Morrow
    772 Morrow
  2. Hiram S Cody III
    242 Cody
  3. Mary L Gemignani
    218 Gemignani
  4. Michelle Moccio Stempel
    153 Stempel