Hidden estrogen production from ovarian remnants leading to progression of disease in metastatic breast cancer Journal Article
| Authors: | Weiner, A.; D'Andrea, G. M. |
| Article Title: | Hidden estrogen production from ovarian remnants leading to progression of disease in metastatic breast cancer |
| Abstract: | In premenopausal women with hormone dependent breast cancers, ovarian suppression is an important part of treatment, and is often achieved with a bilateral salpingo-oophorectomy (BSO). However, this procedure can lead to ovarian remnant syndrome (ORS), a rare condition where the adnexal tissue is not completely removed and can produce estrogen. We describe a case of ORS in a patient with estrogen receptor positive (ER+) breast cancer who had progression of disease after undergoing a BSO, despite optimal therapy. ORS therefore poses a significant treatment challenge in premenopausal ER+ breast cancer patients thought to be rendered menopausal with a BSO. © 2018 Wiley Periodicals, Inc. |
| Keywords: | metastatic breast cancer; ovarian remnant syndrome; er positive breast cancer |
| Journal Title: | Breast Journal |
| Volume: | 24 |
| Issue: | 4 |
| ISSN: | 1075-122X |
| Publisher: | Wiley Blackwell |
| Date Published: | 2018-07-01 |
| Start Page: | 642 |
| End Page: | 643 |
| Language: | English |
| DOI: | 10.1111/tbj.12972 |
| PROVIDER: | scopus |
| PUBMED: | 29357201 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 August 2018 -- Source: Scopus |
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