Binding reactions: epigenetic switches, signal transduction and cancer Journal Article
| Author: | Ptashne, M. |
| Article Title: | Binding reactions: epigenetic switches, signal transduction and cancer |
| Abstract: | Simple binding interactions lie at the heart of disparate biological functions. Multiple negative and positive 'add-ons', often with small individual effects, make elementary systems that work, work better. Cancer illustrates various of these fundamental processes gone awry. © 2009 Elsevier Ltd. All rights reserved. |
| Keywords: | signal transduction; genetics; mutation; pathophysiology; methodology; neoplasm; neoplasms; metabolism; protein kinases; enzymology; physiology; gene expression regulation; gene expression regulation, neoplastic; dna; epigenesis, genetic; dna, neoplasm; short survey; molecular biology; genetic epigenesis; protein kinase; dna directed rna polymerase; dna-directed rna polymerases |
| Journal Title: | Current Biology |
| Volume: | 19 |
| Issue: | 6 |
| ISSN: | 0960-9822 |
| Publisher: | Cell Press |
| Date Published: | 2009-03-24 |
| Start Page: | R234 |
| End Page: | R241 |
| Language: | English |
| DOI: | 10.1016/j.cub.2009.02.015 |
| PUBMED: | 19321137 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 4" - "Export Date: 30 November 2010" - "CODEN: CUBLE" - "Source: Scopus" |
