Isolated portal vein involvement in pancreatic adenocarcinoma: A contraindication for resection? Conference Paper
| Authors: | Harrison, L. E.; Klimstra, D. S.; Brennan, M. F. |
| Title: | Isolated portal vein involvement in pancreatic adenocarcinoma: A contraindication for resection? |
| Conference Title: | 116 Annual Meeting of the American Surgical Association |
| Abstract: | Objective: This study was designed to examine the morbidity, mortality, and survival of patients undergoing portal vein resection (PVR) for adenocarcinoma of the pancreas. Summary Background Data: Inability to separate the pancreas from the portal vein has historically been a locoregional contraindication for resection in patients with adenocarcinoma of the pancreas, and frequently, isolated local invasion of the portal vein is the only obstacle to curative resection. Methods: A review of the prospective database for adenocarcinoma of the pancreas at Memorial SloanKettering Cancer Center identified 332 patients who underwent pancreatic resection. Of those, 58 (17%) were identified as having isolated clinical involvement of the portal vein and underwent pancreatic resection with PVR. Patients undergoing curative pancreatic resection without PVR over this same time period comprise the control group. Results: The 5% in-hospital modality rate for PVR was not significantly different from that seen in those patients who did not undergo PVR (3%). Overall median survival for the PVR group was 13 months (range, < 1-109 months), which was not statistically different from those patients undergoing pancreatic resection without PVR (17 months (range, < 1-132months). Conclusions: These results suggest that suspected isolated portal vein involvement should not be a contraindication for pancreatic resection in patients with adenocarcinoma. |
| Keywords: | adult; cancer survival; treatment outcome; aged; middle aged; surgical technique; major clinical study; patient selection; conference paper; pancreas resection; pancreatic neoplasms; adenocarcinoma; vascular neoplasms; cancer mortality; cancer invasion; pancreas adenocarcinoma; liver resection; portal vein; humans; human; male; female; priority journal |
| Journal Title | Annals of Surgery |
| Volume: | 224 |
| Issue: | 3 |
| Conference Dates: | 1996 Apr 18-20 |
| Conference Location: | Phoenix, AZ |
| ISBN: | 0003-4932 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 1996-09-01 |
| Start Page: | 342 |
| End Page: | 349 |
| Language: | English |
| DOI: | 10.1097/00000658-199609000-00010 |
| PUBMED: | 8813262 |
| PROVIDER: | scopus |
| PMCID: | PMC1235378 |
| DOI/URL: | |
| Notes: | Conference Paper -- Export Date: 22 November 2017 -- Source: Scopus |
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