Management of adenocarcinoma of the body and tail of the pancreas Conference Paper


Authors: Brennan, M. F.; Moccia, R. D.; Klimstra, D.
Title: Management of adenocarcinoma of the body and tail of the pancreas
Conference Title: 107th Annual Session of the Southern Surgical Association
Abstract: Objective: The authors examined the resectability, operative morbidity, mortality, and survival of patients with pancreatic adenocarcinoma of the body and tail compared with lesions in the head. Summary Background Data: Adenocarcinoma of the body and tail of the pancreas is characteristically thought of as a disease that presents late and rarely is operable or resectable. Methods: In an 11-year period, 1981 patients were admitted and entered into a prospective database at Memorial Sloan-Kettering Cancer Center with a diagnosis of peripancreatic cancer, 1363 of whom had adenocarcinoma of the pancreas, 75% with lesions in the head and 25% with lesions in the body and tail. Results: Of 271 patients resected, 237 (23%) had lesions in the head and 34 (10%) had body and tail lesions. Perioperative mortality was 4% for patients with pancreatic lesions in the head and 0% for patients with pancreatic lesions in the body and tail. Five-year actuarial survival for body and tail lesions was projected at 14% for 5 years. Actual survival was 19%, with three patients alive for more than 5 years. Conclusions: Adenocarcinoma of the body and tail of the pancreas, although less likely to be resectable at presentation than lesions in the pancreatic head, have similar postresection survival.
Keywords: survival; adult; treatment outcome; aged; aged, 80 and over; middle aged; survival analysis; major clinical study; clinical trial; histopathology; conference paper; pancreatic neoplasms; lymph node metastasis; lymphatic metastasis; prospective study; prospective studies; adenocarcinoma; proportional hazards models; postoperative complication; pancreas adenocarcinoma; pancreatectomy; new york city; statistics, nonparametric; humans; human; male; female; priority journal
Journal Title Annals of Surgery
Volume: 223
Issue: 5
Conference Dates: 1995 Dec 3-6
Conference Location: Hot Springs, VA
ISBN: 0003-4932
Publisher: Lippincott Williams & Wilkins  
Date Published: 1996-05-01
Start Page: 506
End Page: 512
Language: English
DOI: 10.1097/00000658-199605000-00006
PUBMED: 8651741
PROVIDER: scopus
PMCID: PMC1235171
DOI/URL:
Notes: Conference Paper -- Export Date: 22 November 2017 -- Source: Scopus
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  1. Murray F Brennan
    1059 Brennan
  2. David S Klimstra
    978 Klimstra